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Dr. Callery

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  1. DR. CALLERY,  THANK YOU FOR SAVING MY LIFE

  2. I haven't been on this forum for many years so thought I'd give an update.  I had my RNY in 2002, pre-op 273+lb, 5'6", 46 yrs old.  I have never regretted my surgery.  It saved my life.  It has been a wonderful tool despite my challenges over the years.  I am a serious sugar addict and was able to regain slowly 60 lbs..  I still feel some restriction from my pouch thank God, but grazing on food / sugar throughout the day is why I gained weight.  I've had problems with anemia and vitamin deficiencies during times that I didn't consistently take my vitamins which are critical.  My diabetes went away for 14 yrs but returned with my weight regain or possibly because I was destined to eventually get diabetes anyway since I am 65 yrs old.  I am so grateful that I haven't been morbidly obese for the past 18 yrs. Surgery changed my life.

    I am now actively involved in Overeaters Anonymous online zoom meetings to help me with my addiction to sugar and abnormal relationship with food.  It has helped me immensely.  If you are struggling, consider going to OA.  Surgery helps with weight loss but doesn't cure food addiction.

  3. How can I lose weight? I had Gastric on 2010 and have gained 28 pounds. Help!

  4. Hello Dr. Callery!

    i was sleeved 5-12-17.. a few days ago.. I made the mistake to eat what I now think was a dense, heavy soup. I am now feeling like I'm walking around carriyng a Rock for a stomach. I'm afraid I might have unstitched something, i had WLS in Mexico which is why I can't just go to Drs. Office. But I don't want to overreact and end up in the Emergency for something that could just go away on its own. Any advise? Thank You!

  5. Hi Dr. I had the sleeve done one 4-25-17 and I had a hernia also fixed. But I'm having upper abd. Pain when I drink or eat anything.  It really hurts but it only stays for 7sec then goes away.  I don't understand?

  6. Hi Dr. Callery,

    you did my bypass in 2004. I weighed 257 at the time. 12 years later I have kept most of the weight off, I weigh 155. I consider myself a success!

    An endoscopy yesterday shows an ulcer at the surgery site with one or two of the staples in the ulcer(for lack of a better way to describe it.)

    i have been prescribed a protonix. What typically happens next? 

  7. I think I have co-morbidities but they are not diagnosed (PCOS, sleep apnea). My BMI is 41.5. Should I get them diagnosed so my insurance will be less likely to decline me?

  8. Good morning-

    I have my gastric bypass surgery date on 8/9 and yesterday started having sore throat and post nasal drip.  I do not have a fever.  I have been taking a generic Tylenol cold and flu and drinking 80+ ounces of water and also gargling salt water every hour.  I do not want to postpone my surgery as everything is planned.  I do not know what to do as I don't want to complicate my surgery either.  I do have 6 days left and am hoping with the things I am doing it will pass soon.  Not sure if it is allergies or a cold - its mostly sore throat and post nasal drip.  Any help would be appreciated!

  9. I have questions about gastric bypass reversal. Need answers 

  10. Hi dr. Since I saw your last post, have you still seen positive results with weight loss surgery to relieve gastroparesis..any difference between bypass and vsg?

    Thx you,

    Pamela 

  11. Clostridium difficile (c. difficile or c. diff) is a bacterium that can colonize the colon and cause a diarrheal illness. The bacterium is spread by the fecal - oral route (usually due to poor hand washing). It is more common in people who have been on antibiotics for a prolonged period of time. It can be hospital acquired. C. difficilte diarrhea can vary from mild to severe. Finally, C. difficile can be detected with a stool test and is treated with an oral antibiotic. Read more from WebMD: http://www.webmd.com...olitis-overview From: FDA MedWatch <fda@service.govdelivery.com> Date: 02/08/2012 Subject: FDA MedWatch - Proton Pump Inhibitors (PPIs) - Drug Safety Communication: Clostridum Difficile-Associated Diarrhea (CDAD) Can be Associated With Stomach Acid Drugs Proton Pump Inhibitors (PPIs) - Drug Safety Communication: Clostridum Difficile-Associated Diarrhea (CDAD) Can be Associated With Stomach Acid Drugs AcipHex (rabeprazole sodium) Dexilant (dexlansoprazole) Nexium (esomeprazole magnesium) Omeprazole (omeprazole) Over-the-Counter (OTC) Prevacid (lansoprazole) and OTC Prevacid 24hr Prilosec (omeprazole) and OTC Protonix (pantoprazole sodium) Vimovo (esomeprazole magnesium and naproxen) Zegerid (omeprazole and Sodium bicarbonate) and OTC AUDIENCE: Gastroenerology, Family Practice, Consumer ISSUE: FDA notified the public that the use of stomach acid drugs known as proton pump inhibitors (PPIs) may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD). A diagnosis of CDAD should be considered for patients taking PPIs who develop diarrhea that does not improve. The FDA is working with manufacturers to include information about the increased risk of CDAD with use of PPIs in the drug labels. FDA is also reviewing the risk of CDAD in users of histamine H2 receptor blockers. H2 receptor blockers are used to treat conditions such as gastroesophageal reflux disease (GERD), stomach and small intestine ulcers, and heartburn. BACKGROUND: Proton pump inhibitors (PPIs) are marketed under various brand and generic drug names as prescription and over-the-counter (OTC) products. They work by reducing the amount of acid in the stomach. Prescription PPIs are used to treat conditions such as gastroesophageal reflux disease (GERD), stomach and small intestine ulcers, and inflammation of the esophagus. Over-the-counter PPIs are used to treat frequent heartburn. Clostridium difficile (C. difficile) is a bacterium that can cause diarrhea that does not improve. Symptoms include watery stool, abdominal pain, and fever, and patients may go on to develop more serious intestinal conditions. The disease can also be spread in hospitals. RECOMMENDATION: Patients should immediately contact their healthcare professional and seek care if they take PPIs and develop diarrhea that does not improve. Information for Healthcare Professionals: A diagnosis of CDAD should be considered for PPI users with diarrhea that does not improve. Advise patients to seek immediate care from a healthcare professional if they experience watery stool that does not go away, abdominal pain, and fever while taking PPIs. Patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated. Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program: Complete and submit the report Online: www.fda.gov/MedWatch/report.htm Download form or call 1-800-332-1088 to request a reporting form, then complete and return to the address on the pre-addressed form, or submit by fax to 1-800-FDA-0178 Read the MedWatch safety alert, including a link to the FDA Drug Safety Communication, at: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm290838.htm
  12. Vertical Sleeve Gastrectomy Originally posted January 20, 2012 Updated October 28, 2012 Overview The sleeve gastrectomy is a newer weight reduction procedure that combines mechanical restriction and neurohormonal effects to help patients achieve significant weight loss. The procedure is very straightforward. Eighty-five percent of the stomach is removed leaving a narrow stomach tube or “vertical sleeve” for the passage of food. There is no rearrangement of the intestines. The vagus nerves that innervate the stomach and pyloric valve that regulates outflow of food from the stomach are left intact. History The sleeve gastrectomy procedure evolved from a two part malabsorption procedure called the duodenal switch (DS). In the DS procedure, a fairly wide gastric sleeve was created, and the small intestine was rearranged to cause calorie malabsorption. Some surgeons opted to perform the DS in two stages for safety reasons. The sleeve was constructed first. Then after initial weight loss the intestinal rearrangement was performed. Some of the patients did so well after construction of the sleeve that they did not need to go on to the second part. Thus the concept of the sleeve gastrectomy as a stand alone procedure was born. The diameter of the sleeve used as part of the sleeve/DS procedure was about 20 mm in diameter. Surgeons subsequently found that their patients could lose more weight if the sleeve diameter was decreased to about 13 mm. There is continuing discussion among surgeons as to the best diameter for the sleeve. The tighter the sleeve, the more restriction and perhaps more weight loss. However a tighter sleeve may lead to more complications. So a balance is needed. A consensus will evolve as more reports are published in surgical journals. The American Society for Metabolic and Bariatric Surgery (ASMBS) released a white paper on the sleeve in October 2011. The paper can be downloaded here. The ASMBS supports the vertical sleeve gastrectomy as a primary bariatric surgery procedure based on results gathered to date. As a counterpoint, some authors feel that information gathered so far is insufficient to recommend sleeve gastrectomy as a standalone primary operation. Victorzon writes in a review of current literature: “In conclusion, the quantity, quality, and consistency of evidence concerning LSG for obesity is low. Most of the current evidence comes from poorly designed nonrandomized controlled trials and case series and therefore, there is not yet enough evidence supporting the recommendation of LSG as a definitive, stand-alone procedure for morbid obesity.” Vertical Sleeve Gastrectomy Procedure The VSG is performed under a general anesthetic using laparoscopic technique in most cases. The abdomen is inflated with carbon dioxide gas. A laparoscope is introduced into the abdomen, and an examination is made of the abdominal organs. The surgeon measures 3 to 6 cm from the pyloric valve along the outer edge of the stomach and places a marking suture. The blood vessels are disconnected from the stomach along the outer or left side of the stomach. Any adhesions are taken down from the back of the stomach. A surgical stapler is used to divide the stomach. The stapler simultaneously places six parallel rows of staples, and then cuts between them. The cut (transection) is started at the marking stitch and carried upward by a series of firings of the stapler to the top of the stomach near the esophagus until the transection is completed. A sizer, called a bougie, is a flexible tube that is inserted into the stomach as the transection is performed. The bougie helps assure that the sleeve has the desired diameter. Optimal bougie diameter is under study. The smaller the diameter of the bougie, the tighter the sleeve, and the more the weight loss. However, the tighter the bougie, the higher the chance of leak and of critical narrowing of the sleeve. Aurora found that the leak rate for a bougie diameter of 40 (13 mm) or greater was 0.6%, while for smaller bougie sizes it was 2.8%. Most surgeons reinforce the staple line in order to decrease chance of leakage from a weak spot in the staple line and to decrease the chance of bleeding from the cut edge of the stomach. The staple line can be reinforced by either oversewing it or by using a buttressing material applied to the stapler. The advantages of reinforcement are investigated in a meta-analysis by Choi. Once the transection is completed, the portion of the stomach that has been excised is removed from the abdomen. The surgeon then checks the staple lines to make sure that there isn’t any bleeding. The gas is removed from the abdomen, and the small skin incisions are closed with stitches under the skin. The skin edges are then glued together. Since the sleeve gastrectomy is a new procedure, experts are still working out the details of the "optimal" procedure. Rosenthal reports on progress to this end. Hospital stay Most patients stay in the hospital for two to three nights after surgery. The length of stay depends on the general health of the patient, recovery from anesthetic drugs, evidence of that there is no bleeding, ability to take liquids, general sense of well being, and the patient’s home situation and support. Recovery Recovery depends to a large part on the patient’s general medical condition before surgery. Although this varies widely, most patients can return to work two to four weeks after surgery. Patients who do heavy lifting at work may want to recover for an additional week or two. It is always better to overestimate time off work than to try to get back to work too soon. Weight Loss Results Vertical Sleeve Gastrectomy Results Author.....Number of patients....Follow-up....Weight Loss Johnston........16.............................5 years......61% EWL* Weiner.............8.............................5 years......- 17 BMI Himpens.........41............................6 years.......53% EWL Bohdjalian......26............................5 years.......55% EWL D’Hondt..........23............................6 years.......56% EWL * EWL: Excess Weight Loss (table extracted from ASMBS white paper on Sleeve Gastrectomy, see above) These weight loss results are encouraging. However the number of patients who have been followed for 5 or more years is still small, so one should be cautious when interpreting the results. There are three recent randomized prospective trials that compare sleeve gastrectomy with gastric bypass. Click on the authors' name to view an abstract (summary) of each article. The first, by Kehagias compares 30 patients with sleeve gastrectomy to 30 patients with gastric bypass followed for 3 years. The authors could find no statistically significant difference in weight loss or overall complication rates between the two procedures. There were only 5 diabetics in each group. So no conclusions could be made regarding the relative effectiveness of the two procedures for diabetes, or for recover from any other comorbidity for that matter. The second randomized trial reported by Lee from Taiwan compares the effect of gastric bypass to sleeve gastrectomy on relief from diabetes in low BMI patients. The study was designed to look at the results and mechanism of action of the two surgeries specifically on diabetics. There were a total of 60 patients in the trial, evenly divided between the two procedures. After two years the gastric bypass group achieved significantly better results. The third randomized trial reported by Woelnerhanssen compared the effects of gastric bypass to sleeve gastrectomy on metabolic measurements made during the first year after surgery. There were 12 and 11 patients in each group respectively and they were all non-diabetic. Both groups saw significant weight loss, decrease in serum leptin levels, increase in adiponectin levels, and improved insulin sensitivity. There were no statistically significant differences in these results between the bypass and sleeve groups. These results are important, but the reader should be cautioned to take them at face value and not draw overreaching conclusions. The numbers of patients in each group is small and the follow up period is short. Whether these differences will hold up over the long run and whether the differences will be apparent in higher BMI patients remains to be seen. Relief from Comorbid Medical Conditions Results Type II Diabetes Mellitus In a landmark randomized prospective trial from the Cleveland Clinic Schauer reported that at one year sleeve gastrectomy and gastric bypass were significantly more effective than optimized medical therapy for the treatment of moderate to severe diabetes. Similar results have been found in several less scientifically rigorous studies: Nocca, Abbatini, Leonetti, and Hady. Vertical Sleeve Gastrectomy Risks and Complications Vertical sleeve gastrectomy is major surgery that is performed on patients who are often in poor medical condition. While many complications can be prevented by thorough preparation of the patient before surgery, skillful anesthesia, and careful surgery, some complications will occur anyway. Major early complications include bleeding from the staple line requiring transfusion or possible reoperation (1%), staple line leaks (2.4%), and blood clot to the lungs (0.3%). In rare instances the sleeve can be too tight because of a partial twist or because of scarring. Other very uncommon post op problems include injury to the spleen, pancreatitis, and portal vein thrombosis (0.7%). The mortality rate after vertical sleeve gastrectomy has been reported in the range of 2/1000. Causes of death include pulmonary embolism (blood clot to the lungs), infection following leaks, pneumonia, cardiac irregularities or heart attack, stroke, and other rare events. Long term problems can include development esophageal reflux, sleeve dilation with resultant decrease of restriction, and rarely bowel obstruction due to adhesions (scars inside of the abdomen). Vitamin deficiency can occur if patients do not eat a healthy diet and do not take certain vitamin supplements. These supplements include multivitamins, B12, and in some cases iron. Other vitamins may be necessary. Vitamin levels can be checked with blood tests, so long term deficiencies can be prevented. Esophageal reflux One of the problems that some patients face after sleeve gastrectomy is the development of esophageal reflux. Reflux causes heartburn and esophagitis. It may occur soon after sleeve gastrectomy or may appear after several years. There are probably several causes for reflux, and the problem has not been extensively researched. The sleeve itself can be obstructive. It is a long narrow tube. If it is too tight, it may not function well. Second, the upper part of the sleeve may dilate slowly creating a small pouch. The pouch narrows into the sleeve. Food can accumulate in the pouch and reflux. Third, a patient may develop problems with motility of the esophagus or with the sphincter muscle between the esophagus and stomach. And fourth, some patients may develop a hiatus hernia over time. A hiatus hernia is a widening of the diaphragm at the point where the esophagus passes from the chest into the abdomen. When a hiatus hernia develops, the stomach slips into the chest and the sphincter muscle at the end of the esophagus becomes less effective. Reflux occurs when the sphincter is weak. The first line of treatment for reflux is use of acid blockers and avoidance of acid stimulating foods. A hiatus hernia can be repaired. If antacids don’t work, the sleeve gastrectomy can be converted to a gastric bypass, usually by a laparoscopic approach. Here are the abstracts from two medical journal articles that discuss esophageal reflux following sleeve gastrectomy: Langer, Keidar. Staple line leak Staple line leaks occur infrequently in all abdominal surgeries where staples are used to divide and/or connect bowel. Leaks have been reported to occur in 0 – 4% (2.4% average) of sleeve gastrectomy cases. The cause of staple line leaks is usually an area of tissue weakness somewhere along the staple line. When the weakened tissue breaks down, fluid from within the stomach leaks out into the peritoneal cavity causing an infection. Treatment of leaks has traditionally involved surgical or x-ray guided drainage of the leak, antibiotics, and intravenous or enteral (intestinal) nutrition. Various techniques are often used to reinforce the staple line, but none is completely effective. After the infection associated with a leak is controlled, the next goal is to get the leak to heal. 90% of sleeve leaks occur at the top of the staple line. This location is vulnerable because the narrowness of the sleeve causes a high pressure zone at the upper end of the sleeve. Because of the high pressure, it is often time consuming and difficult to get the leak to heal. A new technique has been introduced to hasten recovery from sleeve gastrectomy staple line leaks. A self expanding tube called a stent can be introduced into the sleeve using an endoscope. The stent expands to close the leak. The stent is hollow allowing passage of food into the stomach during the healing process. Here is a report of three patients treated successfully with stents: Nguyen. Bleeding The incidence of staple line bleeding requiring a transfusion is about 1% following vertical sleeve gastrectomy. Bleeding most often occurs from the staple line. It can also occur from vessels in the abdominal wall that may be punctured by the laparoscopic instruments, from the spleen, or from the blood vessels of the omentum where it is divided from the stomach. many surgeons will either oversew the staple line or use reinforcement materials on the staple line. Most surgeons find that use of these techniques reduces bleeding. For more information see this abstract by Dapri. Almost all patients who undergo obesity surgery are placed on low doses of blood thinners before surgery to prevent blood clots that can go to the lungs. A side effect of the blood thinners is a bleeding tendency. Fortunately bleeding is uncommon and the blood thinners are quite effective at reducing risk of blood clots. It would be extremely unlikely for a patient to die from staple line bleeding with the availability of modern blood banking. If a patient will not accept a blood transfusion because or religious reasons, the surgeon might recommend early return to the operating room to stop the bleeding surgically rather than run the risk of a fatality due to blood loss. Micronutrient Deficiencies Vitamin and mineral deficiencies have been documented after all bariatric surgical procedures. 40-60% of patients have deficiencies before surgery due to inadequate diet and lack of sun exposure (vitamin D). After bariatric surgery, the chance of deficiencies increases unless the diet is carefully chosen and unless patients take appropriate vitamin and mineral supplementation. Studies are just beginning to be published on the effects of sleeve gastrectomy on vitamin and mineral levels. Removal of much of the stomach eliminates the churning, mixing, and breakdown effect on food. Enzymes and acids secreted by the stomach decrease. A chemical called Intrinsic Factor, necessary for the absorption of B12, is produced by the stomach and is therefore decreased after sleeve gastrectomy. Danns-Machado reports, “LSG had a modest effect on micronutrient status by further reducing iron, vitamin B12, vitamin B6, and folate within the first year after intervention.” He goes on to state, “Our data suggest that especially obese patients with preoperative deficits require control and supplementation of micronutrients and protein in the postoperative period.” Vitamin B1 deficiency is uncommon but can cause serious and permanent neurological injury. Three recent reports and one older report of B1 deficiency have been published: Scarano, Moize, Jeong, and Makarewicz. It thus seems imperative that a patient discuss B1 supplementation and measurement of whole blood B1 levels with their surgeon. Vitamin D levels and other micronutrient levels were followed for up to 5 years by Saif. This study found that “The vitamin D level was less than normal in 42% of the patients at year 5. After normalization from baseline, by year 5, parathyroid hormone had increased in 58.3% of patients. At year 5, vitamin B(1) was less than normal in 30.8% of patients, and hemoglobin and hematocrit were less than normal in for 28.6% and 25% of patients, respectively.” What they also found was that many patients failed to take vitamin and mineral supplements: “28.9% of patients reported taking supplements in year 1, 42.9% in year 3, and 63.3% in year 5.” Once again this study shows that vitamin and mineral deficiencies are common, and it is imperative for patients to take vitamin and mineral supplementation recommendations to heart. Dumping syndrome Patients may develop "dumping syndrome" as a reaction to sweet foods after a wide range of stomach surgeries. When a person with normal anatomy consumes sweet food or drink (think cheesecake or fruit smoothies), the food is gradually released from the stomach into the small intestine. Following a stomach surgery, the food is released more quickly, and the sugars or fats can overwhelm the ability of the small bowel to handle it. The result is a syndrome that often includes a hot flash, nausea, weakness, sometimes diarrhea, sometimes hypoglycemia, and other symptoms. For a full discussion of dumping syndrome download the article attached at the bottom. Dumping syndrome occurs when the stomach empties its contents more rapidly than usual. Rapid emptying is thought to occur after sleeve gastrectomy as cited by Melissas. The first study to systematically test sleeve patients for dumping was published in October 2012 by Papamargaritis. He found that dumping occurred in 40% of sleeve patients at 6 months after surgery and 33% at 12 months. Mild dumping syndrome can act as a deterrent to help patients avoid very sugary foods. Moderate or severe dumping can be very problematic. Dumping syndrome can be minimized by keeping the sugar and concentrated fat content of meals low, by keeping meals small, by not drinking liquids with meals, and by waiting to drink liquids for 30 minutes after a meal. Conclusion Vertical sleeve gastrectomy is a new weight loss surgery that has become popular in the last few years. Early reports suggest that weight loss results will probably fall between those of the adjustable gastric band and gastric bypass. The sleeve gastrectomy is appealing because of its apparent simplicity. There are several problems that can follow gastric bypass that are not seen with the sleeve. These include anastomotic ulcers and bowel obstructions. However, it appears that vitamin deficiencies and dumping syndrome are common after both procedures. Since there is so little long term data for the sleeve, we do not yet know the results at 5 or 10 years for reduction of diabetes, obstructive sleep apnea, or hypertension compared with gastric bypass. Finally, we do not know how big an issue late development of esophageal reflux will become. We look forward to the medical reports that will be forthcoming in the next few years.
  13. Call your surgeon. Can't give personal medical advice.

  14. The International Diabetes Federation released a position paper on the application of surgery to the treatment of Type 2 Diabetes Mellitus on March 28, 2011. The paper offers a comprehensive overview of the current thinking on effectiveness of surgery, cost-effectiveness, eligibility guidelines, risks, comparison of procedures, and place of bariatric procedures in the plan or algorithm for the treatment of diabetes. Please visit the International Diabetes Federation web page and download the paper. It is the current gold standard summary of the field and well worth reading carefully by any diabetic patient considering surgery.
  15. FDA warns PPIs may deplete magnesium The FDA has issued a warning that the regular use of proton pump inhibitors (PPIs) for a year or longer may lead to low levels of circulating magnesium, which may increase the risk of leg spasms, arrhythmias, and seizures. The FDA noted that PPI-associated hypomagnesemia was generally reversed with magnesium supplements, but in about 25% of cases "magnesium supplementation alone did not improve low serum magnesium levels and the PPI had to be discontinued." The FDA's notice included the prescription drugs: esomeprazole magnesium (Nexium), dexlansoprazole (Dexilant), omeprazole (Prilosec), omeprazole and sodium bicarbonate (Zegerid), lansoprazole (Prevacid), pantoprazole sodium (Protonix), rabeprazole sodium (AcipHex) and the combination product esomeprazole magnesium/naproxen (Vimovo). Also included were OTC formulations of the drugs: Prilosec OTC, Zegerid OTC, and Prevacid 24-hour. The FDA says physicians "should consider obtaining serum magnesium levels prior to initiation of prescription PPI treatment in patients expected to be on these drugs for long periods of time." Also, the risk of hypomagnesemia may be greater when PPIs are given to patients who are already taking drugs that are known to deplete magnesium, including digoxin and diuretics. The FDAs warning follows previous reports regarding PPI use and their potential increase in risk for heart attack or stroke with patients who have undergone stenting and other percutaneous cardiovascular events. In addition, there have been reports linking PPI use to increased risk of Clostridium difficile diarrhea. Click to read FDA Warning Credit for this summary goes to the Sharp Memorial Hospital Pharmacy news letter
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